Stephen Lloyd, Ph.D.
Dr. Lloyd’s academic career has been evenly distributed at three university medical schools, including Vanderbilt University, The University of Texas Medical Branch (UTMB), and Oregon Health & Science University, where he is currently a Professor in the Department of Molecular and Medical Genetics, and the Associate Director of Basic Research for the Oregon Institute of Occupational Health Sciences. After earning his Ph.D. at the University of Texas, MD Anderson Hospital, postdoctoral training at Stanford University, and working for a genetic engineering company, Genex Corporation, he was recruited to the Department of Biochemistry at Vanderbilt, rising through the academic ranks to Professor. He was then recruited to join the Sealy Center for Molecular Science at UTMB, where he was the first director of their NIEHS P30 Center and headed the Sealy Center in Environmental Health and Medicine. In 2003, Dr. Lloyd and Dr. Amanda McCullough had the opportunity to join OHSU, where their laboratories focus on DNA repair and mutagenesis. The primary emphasis of their investigations is to translate and apply basic science knowledge to clinically germane therapeutics. For several decades, their work has laid the foundation for prevention of sunlight-induced skin cancers through enhancement of the DNA repair capacity of skin cells. Their laboratories are well funded with several NIH grants that include other investigations in prevention of environmental carcinogenesis and improved clinical therapeutics.
Amanda K. McCullough, Ph.D.
Dr. McCullough is an Associate Professor in the Department of Molecular and Medical Genetics and the Oregon Institute of Occupational Health Sciences and is a member of the Knight Cancer Institute, Cancer Biology Program. She is currently serving as Vice Chair of Basic Sciences and co-Director of the Graduate Program for Molecular & Medical Genetics and Director of the Genome Sciences Hub in the Program in Biomedical Sciences. Dr. McCullough earned her Ph.D. in Cellular and Molecular Biology from the University of Vermont. She completed postdoctoral training in the Division of Hematology & Medical Oncology at Oregon Health & Science University and in the Department of Human Biological Chemistry & Genetics at the University of Texas Medical Branch. Her research is focused on the translation of fundamental basic science discoveries of cellular DNA damage response pathways into actionable clinical interventions and improved therapeutic response. In collaboration with Stephen Lloyd, she has studied the DNA repair of UV-induced DNA lesions for over 20 years and has contributed both mechanistic biochemistry and cell biology to the field and recently extended these investigations to pre-clinical models of human therapeutics.